RNA Details
Disease Name
skin fibrosis
Tissue
skin
RNA Symbol
mir-130b
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
immunofluorescence etc.
Target
MICRORNA-130B
Pathway
NA
PubMed ID
Title
MicroRNA-130b regulates scleroderma fibrosis by targeting peroxisome proliferator-activated receptor gama
Year
2015
Function
"These studies demonstrated that mir-130b played important profibrotic roles in ssc fibrosis, and enhanced tgf-beta signaling through negative regulation of ppar_gama expression. Mir-130b may be a potential therapeutic target in ssc fibrosis."